All missables in Resident Evil 4
Everything you can permanently miss, in the order you reach it: where it is, how to get it and what locks it out.
| Item | Area | Where and how | What locks it out | |
|---|---|---|---|---|
| Kitchen Knife | Lakeside Settlement | From the entrance gate of the Lakeside Settlement, head northeast into the main yard toward the dilapidated sheds to find an old wooden pushcart.How: Approach the left wooden wheel of the cart and interact with the blade stuck into the wood to pick it up. | permanently locked out once you cross the lake at the end of Chapter 4, as you cannot return to the village areas. | |
| Pearl Pendant | Lakeside Settlement | From the wooden pier dock at the Lakeside Settlement, walk up the path into the center of the area to locate the contaminated well surrounded by wooden fencing.How: Shoot the wooden support stick holding the well cover open so it drops down, then shoot the hanging silver lantern above it and collect the treasure from the closed lid. | permanently locked out once you cross the lake at the end of Chapter 4, as you cannot return to the village areas (and shooting the lantern while open turns it into the Dirty Pearl Pendant). | |
| Small Key | Lakeside Settlement | From the rear locked Insignia gate of the Lakeside Settlement, follow the dark tunnel north to the Forest Altar cavern and look along the wooden fence overlooking the cliffside.How: Walk up to the wooden wagon parked against the fence and pick up the key resting on top of its flatbed. | permanently locked out once you cross the lake at the end of Chapter 4, as you cannot return to the village areas. | |
| Gold Bar | Lakeside Settlement | From the main yard of the Lakeside Settlement, enter the northernmost house requiring the Insignia Key, turn left into the side room, and approach the wooden desk.How: Interact with the locked desk drawer and unlock it using a Small Key from your inventory. | permanently locked out once you cross the lake at the end of Chapter 4, as you cannot return to the village areas. | |
| Wayshrine Treasure (Splendid Horn) | Lakeside Settlement | From the water's edge at the Lakeside Settlement, head toward the stone cliff wall on the west side of the area to locate the locked stone Old Wayshrine.How: Interact with the wayshrine and unlock its stone doors using the Old Wayshrine Key obtained at the Mural Cave. | permanently locked out once you cross the lake at the end of Chapter 4, as you cannot return to the village areas. | |
| W-870 Shotgun | Village Square | Enter the two-story house directly across the path from the central bonfire, head up the stairs, and look on the wall immediately to your right.How: Interact with the shotgun mount to take it off the wall. | permanently locked out once you cross the bridge to the Castle at the end of Chapter 5. | |
| Hand Grenade | Village Square | Enter the two-story house directly across the path from the central bonfire, go up the stairs to the second floor, and look to the glass display case mounted to the right of the bed.How: Break the glass cabinet with a knife strike or gunshot, then pick up the grenade. | permanently locked out once you cross the bridge to the Castle at the end of Chapter 5. | |
| Ruby | Village Square | From the central bonfire, head along the northeast path toward the barred exit gate and enter the small wooden shack on your right to find a small jewelry box on the table.How: Open the small jewelry box on the table to collect the Ruby. | permanently locked out once you cross the bridge to the Castle at the end of Chapter 5. | |
| Velvet Blue | Village Square | From the second floor of the two-story house across from the central bonfire, climb out the window onto the external wooden awning and follow the rooftop around to the far corner.How: Pick up the item sitting openly on the wooden rooftop surface. | permanently locked out once you cross the bridge to the Castle at the end of Chapter 5. | |
| Blue Request Note: Pest Control | Farm | From the typewriter save point house in the Farm, head north across the field to the wooden gate blocking the path to the bridge, where the blue paper hangs on the wall beside the gateHow: Approach the blue paper tacked to the wall and press the interact button to accept the request | lost once you complete Chapter 4 and cross into the Castle at the end of Chapter 5 | |
| Flanged Mace | Farm | From the northern gate of the Farm, look directly south along the stone wall to find the locked wooden Wayshrine cabinetHow: Backtrack here in Chapter 3 or 4 after retrieving the Old Wayshrine Key from the Mural Cave, interact with the shrine, and select the Old Wayshrine Key to open it | lost once you progress past Chapter 5 into Chapter 6, as you cannot return to the Village area | |
| Pearl Pendant | Farm | From the windmill generator building on the western side of the Farm, walk behind it to the dirty well equipped with an open water tank and a swinging metal counterweightHow: Shoot the wooden block holding the well cover open so it covers the filthy water, wait for the lantern holding the pendant to swing over the covered side, and shoot the lantern down to collect the clean pendant | permanently degraded into a Dirty Pearl Pendant if shot into the dirty water, and lost entirely once you pass the point of no return at the end of Chapter 5 | |
| Small Key | Farm | From the southern entrance gate of the Farm, enter the small open shed located just southwest of the large barnHow: Walk inside the shed and pick up the Small Key resting on the tabletop of the wooden desk | lost once you pass the point of no return at the end of Chapter 5 | |
| Kitchen Knife | Abandoned Factory | From your cell in the Abandoned Factory basement where you wake up chained to Luis in Chapter 2, walk down the corridor into the open room and look at the vertical wooden support beam near the workbench.How: Approach the wooden post and pick up the knife embedded in it. | missable because you cannot return to this lower section of the Abandoned Factory once you progress through the valley and cross the lake later in the chapter. | |
| Small Key | Abandoned Factory | From the Merchant's station right outside the Abandoned Factory, re-enter the facility's northern control room past the furnace room and check the brown filing desk against the south wall.How: Open the small briefcase/drawer resting on top of the desk to take the key. | missable because progressing past the point of no return at the end of Chapter 4 locks off the Village area entirely. | |
| Small Key | Village Chief's Manor | from the front door of the manor, head through the living room into the dining area at the southwest corner and look on top of the small low side tableHow: pick up the key resting next to the table lamp | lost permanently once you finish Chapter 5 by crossing the bridge to the Farm with Ashley | |
| Clockwork Castellan (Chapter 2) | Village Chief's Manor | hidden behind a breakable curtain and wooden crate in the attic accessible via the bedroom ladder | Being checked | |
| Small Key | Valley | From the locked gate requiring the Hexagonal Emblem at the south side of the Valley, head into the small wooden shack immediately to the right to find an open lockbox on a tableHow: Interact with the open lockbox to pick up the key | permanently locked out once you cross the lake at the end of Chapter 4 | |
| Ruby | Valley | From the roof of the central elevated building where you collect the Hexagonal Emblem, follow the wooden walkway north into the attached hilltop shack to find a small ornate chest on a tableHow: Open the ornate wooden chest to take the gem | permanently locked out once you cross the lake at the end of Chapter 4 | |
| Flagon | Valley | From the rooftop where the Hexagonal Emblem is placed, walk out onto the back exterior wooden scaffolding behind the northern structure to find a small treasure chestHow: Open the ornate chest | permanently locked out once you cross the lake at the end of Chapter 4 | |
| Yellow Herb | Valley | From the initial drop-off ledge entering the Valley, enter the first wooden shack immediately on your right (west side) to find a tableHow: Pick up the potted herb sitting on the table | permanently locked out once you cross the lake at the end of Chapter 4 | |
| Hexagon Piece B | Fish Farm | From the fuel shed at the far north of the Fish Farm, head southwest through the knee-deep water underneath the wooden walkways to find a red chest tucked under the platform.How: Open the red chest. | Lost once you cross the lake and advance past Chapter 4, as the village lake area becomes permanently inaccessible later. | |
| Small Key | Fish Farm | From the fuel shed at the northernmost point of the Fish Farm, turn around and enter the small shack directly southwest of it to find a desk with an open drawer.How: Pick up the key from inside the wooden desk drawer. | Lost once you advance past Chapter 4, closing off access to the lake and Fish Farm. | |
| Ruby | Fish Farm | From the central wooden ramp in the middle of the Fish Farm, look up at the underside of the elevated wooden bridge walkway overhead to spot a hanging silver bell.How: Shoot down the silver bell and pick up the Ruby from the water where it lands. | Lost once you advance past Chapter 4, which seals off access to the village lake regions. | |
| Antique Pipe | Fish Farm | From the tunnel exit leading from the Fish Farm back to the Merchant's cave dock, approach the wooden Wayshrine built into the cliff wall along the path.How: Unlock the Wayshrine using the Old Wayshrine Key. | Lost once you advance past Chapter 4, permanently locking out the village section of the game. | |
| Lunker Bass | Fish Farm | From the Boatclearing dock next to the lakeside Settlement, face the open water toward the southeast near the boathouse to spot a massive fish swimming near the surface.How: Throw a harpoon from the boat at the swimming fish and drive over it to collect it. | Lost once you defeat El Gigante and conclude Chapter 4, locking out the lake and its Merchant requests. | |
| Pearl Pendant | Lakeside Settlement (Chapter 3) | From the dock at Lakeside Settlement, head past the central houses to the open dirt courtyard containing a covered wellHow: Shoot the wooden stick propping open the well lid so it drops shut, then shoot the silver bell hanging from the windmill frame above so it lands on the cover | Shooting the lantern while the well is open permanently soils the pendant into a dirty version with significantly reduced value, and the area becomes inaccessible after Chapter 5 | |
| Small Key | Lakeside Settlement (Chapter 3) | Inside the house behind the locked Insignia door, sitting on a desk in the main room | Being checked | |
| Officer's Cap | Lakeside Settlement (Chapter 3) | Inside the hidden subterranean cavern unlocked with the Insignia KeyExact spot: being checkedHow: Open the container or pick it up from its location in the cavern | Locks out after Chapter 5 when leaving the Village area | |
| Blue Medallion | Quarry | From the open center of the Quarry, look up toward the upper wooden scaffolding and walkways lining the rock walls.How: Aim upward at the suspended wooden beam and shoot the dangling blue medallion. | lost once you finish Chapter 5, as crossing into the Castle at the end of the chapter locks you out of the Village region permanently. | |
| Blue Request Note: "Viper Hunter" | Quarry | From the Quarry exit tunnel, follow the path toward the Fish Farm and look at the wooden wall right beside the Merchant's shop doorway.How: Interact with the blue sheet of paper pinned to the wall to accept the request. | lost once you finish Chapter 5, as advancing past the Village locks out all remaining Village requests. | |
| Small Key | Church | Inside the Church, head to the right of the pulpit to find a small open side room, where the key rests on top of a low table next to a typewriterHow: walk up to the table and pick up the key | permanently locked out once you cross the bridge to the Slaughterhouse at the end of Chapter 5. | |
| Blue Dial | Church | Inside the Church, head down the hallway to the left of the pulpit to find a large wooden cabinet at the far dead endHow: open the cabinet doors and pick up the dial inside | not missable (required puzzle item to rescue Ashley). | |
| Blue Medallions request note | Castle Gate | from the entrance gate of the castle, head past the Merchant to the large wooden double doors leading inside the Castle Gate area, where the blue note is posted on the stone wall directly to the right of the archwayHow: interact with the blue paper hanging on the wall to accept the "Destroy the Blue Medallions 3" request | permanently locked out once you complete Chapter 12 and take the boat to the Clock Tower/Island | |
| Elegant Perfume Bottle | Castle Gate | from the cannon platform, look for the hole in the floor near where you cranked the cannon, drop down into the lower room, and walk to the northern alcove to find a treasure chestHow: open the ornate wooden chest with an assist from Ashley to boost over or directly interact with the latch | permanently locked out once you complete Chapter 12 and leave the castle region | |
| Beryl | Castle Gate | from the cannon platform, walk along the southeastern defensive walkway toward the circular stone tower until you reach the archway directly preceding the catapult rampartsHow: aim up at the ceiling of the archway and shoot down the hanging silver lantern container, then collect the gem from the floor | permanently locked out once you complete Chapter 12 and leave the castle region | |
| Small Key | Castle Main Hall | From the headless chimera statue in the Grand Hall, take the northern door on the upper walkway toward the Armory, head to the end of the corridor, and find a wooden desk on the rightHow: Open the drawer of the wooden desk | Locked out after boarding the boat with Ashley at the end of Chapter 12 to leave the Castle for the Island | |
| Yellow Herb | Castle Main Hall | From the Grand Hall Merchant room entrance on the ground floor, walk past the southern staircase leading up to the balcony and look into the recessed alcove beneath those stairsHow: Pick it up directly from the floor near the wooden support pillar | Locked out after boarding the boat with Ashley at the end of Chapter 12 to leave the Castle for the Island | |
| Clockwork Castellan | Castle Main Hall | From the headless chimera statue on the upper level of the Grand Hall, run to the far northwest corner of the mezzanine behind the decorative partition wallHow: Look down behind the partition screen and shoot the winding figurine resting on the floor | Locked out after boarding the boat with Ashley at the end of Chapter 12 to leave the Castle for the Island | |
| Iron Sword | Treasury | In the Treasury room with the four mural reliefs, look at the second relief from the left depicting a battle sceneHow: Interact with the relief to pull the sword out of the slot | not missable, as collecting and placing all four swords is required to open the gate and progress Chapter 7 | |
| Golden Sword | Treasury | In the Treasury room with the four mural reliefs, look at the far-left relief depicting a lord receiving homageHow: Interact with the relief to pull the sword out of the slot | not missable, as collecting and placing all four swords is required to open the gate and progress Chapter 7 | |
| Rusted Sword | Treasury | In the Treasury room with the four mural reliefs, look at the far-right relief depicting a fallen warrior/tombHow: Interact with the relief to pull the sword out of the slot | not missable, as collecting and placing all four swords is required to open the gate and progress Chapter 7 | |
| Bloodied Sword | Treasury | In the Treasury, stand in front of the locked iron gate with animal-insignia gongs on the north wall and look through the opened gate into the alcoveHow: Ring the matching deer, eagle, and snake gongs (shoot the ones behind the gate) to open the gate and take the sword resting against the back pedestal | not missable, as collecting and placing all four swords is required to open the gate and progress Chapter 7 | |
| Golden Horn | Treasury | In the Treasury, after opening the four-mural sword gate, enter the short corridor leading toward the Audience Chamber and look for the ornate chest on the left sideHow: Open the ornate treasure chest | locked out once you cross the underground waterway to the Clock Tower at the end of Chapter 12 | |
| Clockwork Castellan | Grand Hall | Grand Hall, take the northern stairs up to the second floor and head south along the balcony all the way to the dead-end archway in the far southern cornerHow: look behind the curtained partition on the floor next to an overturned table and shoot or slash the mechanical doll | lost once you progress to Chapter 10 and lose access to the upper level of the Grand Hall. | |
| Small Key | Armory | from the Armory's ground-floor exit gate, follow the hallway toward the Grand Hall until you reach the small red-carpeted corridorHow: open the small ornate brown box resting on the low wooden cabinet next to the chairs | progressing past Chapter 12 to the Island locks you out of the Castle permanently | |
| Small Key | Water Hall | Inside a small decorative chest in the corridor room just before entering the main Water Hall basinExact spot: being checked | Being checked | |
| Velvet Pewter | Water Hall | From the main ground floor of the Water Hall, look up above the open flooded lower central basin to spot a silver bell suspended from the arched ceilingHow: Shoot the hanging bell down with any firearm and collect the dropped treasure | locked out upon dropping down the pit to the Depths at the end of Chapter 10 | |
| Small Key | Bindery | In the Bindery on the second floor of the Castle, head into the adjacent hallway past the fireplace to the low wooden desk by the windowHow: Pick it up directly from the desk surface | locked out permanently once you drop down the chandelier to the Grand Hall and pass the point of no return at the end of Chapter 12 | |
| Treasure: Ornate Necklace | Castle Battlements | In the Castle Battlements (Chapter 8), start from the switch that flips between sun and moon gates, drop down through the hole in the floor in the central tower, and look against the wall for an ornate treasure chestHow: Open the ornate treasure chest | Point of no return when completing Chapter 12 / taking the clock tower elevator to the Sanctuary. | |
| Clockwork Castellan | Castle Battlements | In the Castle Battlements (Chapter 8), head to the southwest outer tower where the armored El Gigante throws boulders, climb up onto the roof walkway, and look on top of the stacked crates and sandbags at the dead-endHow: Shoot or knife the bobblehead figure | Point of no return when completing Chapter 12 / taking the clock tower elevator to the Sanctuary. | |
| Small Key | Courtyard | From the main center staircase of the Courtyard maze, head north toward the northern outer wall and follow the path west into a dead-end alcove to an open, flat wooden box sitting on a stack of covered cargoHow: Pick up the key from inside the open box | permanently locked out once you complete Chapter 12 and take the boat to the Clock Tower | |
| Clockwork Castellan | Courtyard | From the Courtyard Merchant room, exit through the west door into the Courtyard, head down the stairs, and look behind the stack of crates in the dark alcove directly to the left (south) of the staircaseHow: Shoot or knife the mechanical figurine sitting on the floor behind the pallets | permanently locked out once you complete Chapter 12 and take the boat to the Clock Tower | |
| Elegant Mask | Courtyard | From the southern central tower/switch of the Courtyard maze, follow the path south toward the outer hedge wall and turn east into a narrow dead-end alcove to an ornate treasure chestHow: Open the ornate treasure chest | permanently locked out once you complete Chapter 12 and take the boat to the Clock Tower | |
| Yellow Herb | Throne Room | From the double doors entering the Throne Room in Chapter 12, look immediately to the right at the low wooden table against the wallHow: Pick it up directly from the surface of the table | permanently lost once you take the boat to the Clock Tower at the end of Chapter 12 | |
| Golden Chicken Egg | Throne Room | From Ramon Salazar's throne at the far end of the Throne Room, turn right to face the square lock box sitting on an ornate stand in the cornerHow: Interact with the square lock box, select the Cubic Device, and align its notches to fit the puzzle | permanently lost once you take the boat to the Clock Tower at the end of Chapter 12 | |
| Gold Bar | Clock Tower | From the ground-floor entrance of the Clock Tower, head immediately left past the giant Salazar statue to the red folding screen in the south corner, where an ornate treasure chest sitsHow: Open the ornate treasure chest | Point of no return after completing Chapter 12 and taking the boat from the Castle to the Island. | |
| Clockwork Castellan | Clock Tower | From the ground-floor entrance of the Clock Tower, go straight past the Salazar statue toward the northwest corner where wooden stairs begin, then check beneath the steps on top of a stack of cardboard boxesHow: Shoot and destroy the winding bobblehead figure | Point of no return after completing Chapter 12 and taking the boat from the Castle to the Island. | |
| Alexandrite | Clock Tower | Ascending the wooden scaffoldings of the Clock Tower, look up at the underside of the wooden beam directly beneath the top floor with the rolling spike ball mechanismHow: Shoot the hanging silver bell cage with a firearm to drop the gem to the floor below and pick it up | Point of no return after completing Chapter 12 and taking the boat from the Castle to the Island. | |
| Handgun Ammo | Island Wharf | From the wooden pier where Leon arrives at the Wharf, step onto the stone shore and look immediately to the right against the rock wall for a wooden crate.How: Break the crate with a melee attack or knife strike to collect the ammo. | You cannot return to the Wharf once you cross the point of no return later in Chapter 16, or backtrack once moving past certain one-way drop-offs. | |
| Green Herb | Island Wharf | From the arrival dock, follow the ascending dirt trail past the first rock wall and look along the foliage on the right edge of the path.How: Approach the potted Green Herb on the ground and pick it up. | You cannot return to the Wharf once you pass the point of no return later in Chapter 16. | |
| Red Beryl | Island Wharf | From the first searchlight tower along the cliffside path before the bunker gate, look up at the metal crossbeams hanging over the rocky pathway.How: Shoot the hanging silver bell or cage suspended from the scaffolding and pick up the gem from the ground. | You cannot return to this introductory section of the island once you advance to the final stage of Chapter 16. | |
| Velvet Blue | Encampment | In Chapter 15 at the Stronghold, climb to the metal catwalks directly under the anti-aircraft gun structure to spot a small silver lantern hanging from the scaffolding ceilingHow: Shoot the hanging silver lantern and pick up the dropped jewel | Locked out after passing through the double doors into the Sanctuary Approach, as you cannot backtrack. | |
| Red Beryl | Encampment | In Chapter 15 at the Stronghold, inside the upper control room where you destroy the anti-aircraft gun, look at the small ornate chest sitting on a crate in the northwest cornerHow: Open the ornate wooden chest | Locked out after advancing through the heavy doors into the Sanctuary Approach, as the gate closes behind you. | |
| Blue Medallions | Encampment | In Chapter 15 across the Stronghold (Encampment), hung in five spots: inside the first small bunker on the left, high up on the crane boom above the central path, beneath the metal catwalk railing near the AA gun, inside the ground-floor archway under the gun platform, and off the high cliff edge to the north behind the main ruinsHow: Shoot and destroy all five hanging blue medallions to complete the Merchant request | Locked out once you proceed past the double doors into the Sanctuary Approach, preventing completion before the point of no return. | |
| Biosensor Scope | Specimen Storage | In the Incubation Lab, start from the northern room with the card-overwriting terminal and look directly to the open metal case resting on the counter adjacent to the terminalHow: pick it up from the open case | lost permanently after boarding the cargo lift at the end of Chapter 15, which locks out the laboratory area for the rest of the game | |
| Green Herb | Dissection | From the Dissection room entrance where you restore power, head into the operating area to find it on the tiled floor between the two central operating tablesHow: Pick it up directly from the floor | Lost once you ride the cargo lift at the end of Chapter 15 and trigger the point of no return for the Island. | |
| Handgun Ammo | Dissection | From the operating tables in Dissection, walk south to the glass partition wall to find a wooden barrel resting against the cabinetsHow: Break the wooden barrel with a knife or firearm | Lost once you ride the cargo lift at the end of Chapter 15 and trigger the point of no return for the Island. | |
| LE 5 | Freezer | From the Power Control Lever in the Dissection area in Chapter 13, switch the power route to the right side, enter the Freezer room down the hall to the southeast, and head to the Electronic Lock Terminal on the right side of the roomHow: Solve the terminal's circuit puzzle to open the security door, walk into the small refrigeration chamber, and pick up the weapon sitting on the silver metal tray | locked out permanently once you take the cargo elevator to the Comms Facility at the end of Chapter 15. | |
| Blue Medallion | Waste Disposal | from the entrance of Waste Disposal after reuniting with Ashley, proceed through the first doorway and look south across the toxic drainage canal to the far wallHow: shoot down the blue medallion hanging from the wall above the sewage pipes | lost once you complete Chapter 14 by riding the cargo crane elevator to the Ruins. | |
| Blue Medallion | Waste Disposal | from the central bridge mechanism wheel where Ashley raises the bridge, head north toward the back of the chamber and look into the large square pipe opening above the sludge poolHow: look into the open pipe and shoot the medallion hanging inside it | lost once you complete Chapter 14 by riding the cargo crane elevator to the Ruins. | |
| Blue Medallion | Waste Disposal | from the bridge Ashley raises with the wheel mechanism, cross over it and turn around to look underneath the metal bridge walkway itselfHow: look down into the gap under the raised bridge structure and shoot the medallion dangling below | lost once you complete Chapter 14 by riding the cargo crane elevator to the Ruins. | |
| Blue Medallion | Waste Disposal | from the power breaker console in the southern control room that re-routes power, step outside into the adjacent water-filled alcove and look behind the metal debrisHow: look behind the metal column and shoot the medallion hanging against the wall | lost once you complete Chapter 14 by riding the cargo crane elevator to the Ruins. | |
| Clockwork Castellan | Ruins | In the Cliffside Ruins basement room, look upward through the ceiling rafters directly above the doorway leading out toward the Specimen Storage passageHow: Shoot the bobblehead figurine perched on the wooden crossbeam overhead | Lost once you pass the point of no return at the end of Chapter 14. | |
| Velvet Blue | Ruins | In the Cliffside Ruins subterranean basement, hang right at the ladder to enter the dark archway and look up at the stone ceilingHow: Shoot down the small silver lantern hanging from the ceiling and collect the dropped gem | Lost once you leave the area and progress past Chapter 14. | |
| Crystal Cross | Ruins | In the Cliffside Ruins open combat area, dropped directly by the Boar-masked Brute wielding a war hammer who ambushes youExact spot: being checkedHow: Defeat the Brute and pick up the treasure from his corpse before exiting | Lost once you jump down into the next area and advance past Chapter 14. | |
| Iluminados Emblem | Sanctuary | Placed on the main altar inside the SanctuaryExact spot: being checked | Being checked |
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