NEST 2 (Lab 2)

Resident Evil 3 guide · The final confrontation with Nemesis

Jill enters the underground disposal and railgun facility underneath NEST 2 for the ultimate showdown against Nemesis. She must use the massive Experimental Next-Gen Railgun (FINGeR) to destroy Nemesis's final, mutated mass while manually resetting depleted power cells. Once the creature is destroyed, Jill climbs the lift to the helipad to escape Raccoon City with Carlos.

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File: Weapon Spec Sheet: On a console to the right side of the preparation room before the boss arenaFirst Aid Spray: On the equipment table in the safe room before the final boss arenaHandgun Ammo: On the safe room table just before entering the final boss arenaHandgun Ammo: On the perimeter edge of the boss arena floor

Achievements here

I Might Need These Later! MissableComplete the full game using one or fewer recovery items; the mandatory scripted Green Herb after the Clock Tower fight counts as one.

Bookworm MissableCollect and read all 56 story files scattered across the campaign. You must pick them up as you advance, as earlier areas become inaccessible once you proceed past major story points.

Minimalist MissableFinish the entire game without opening the item box a single time. This is best attempted on Assisted difficulty since you start with extra inventory slots and health regeneration.

Goodbye, Charlie! MissableFind and destroy all 20 Charlie Doll bobbleheads hidden throughout the game. Ensure you destroy each one before leaving its respective area, as past zones are cut off permanently.

Nemesis Down?Complete all major story encounters and put an end to Nemesis once and for all.

SurvivorBeat the main campaign on "Standard" difficulty or higher.

VeteranComplete the main story campaign on "Hardcore" difficulty or higher.

SprinterFinish the entire game in under 2 hours total in-game playtime.

Sensational Work!Finish the campaign with an S rank on any difficulty by meeting the specific clear time and save limits. This is easiest on Assisted difficulty or by using shop items like the infinite rocket launcher.

ConquerorComplete the entire campaign on Nightmare difficulty or higher. This difficulty mode is unlocked after finishing the game once on Hardcore.

DominatorComplete the campaign on the highest difficulty setting, Inferno mode. Inferno difficulty is unlocked after completing a playthrough on Nightmare.

Jill ValentineComplete the game with an S rank on Inferno difficulty. You must finish the campaign in under 2 hours with 5 or fewer saves and without using continues.

Achievement guide and roadmap →

Enemies

Nemesis (Final Form)

Weak to Glowing orange pustules / weak points

Fires acid and slams massive tentacle appendages across the arena; shooting all glowing pustules temporarily stuns him so power cores can be pushed in

Tips

Fire the railgun immediately at the start of the battle to stagger Nemesis, which causes the arena's power units to overload and pop out.
You must destroy every glowing orange blister on Nemesis's body before attempting to push in the red power generator cores, as his attacks will instantly interrupt you.
On higher difficulties such as Nightmare and Inferno, Nemesis can perform multi-hit stun-lock combos with his tentacles; mastering the perfect dodge is essential to survive.
After completely obliterating Nemesis with the final railgun shot, turn around and grab the ladder to reach the exit lift leading to the final cutscene.

Not listed for this area: secrets, shops and people.

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NEST 2 (Lab 1)

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