Guides / Mass Effect 2 (Legendary Edition)
All missables in Mass Effect 2
Everything you can permanently miss, in the order you reach it: where it is, how to get it and what locks it out.
| Item | Area | Where and how | What locks it out | |
|---|---|---|---|---|
| Medi-gel | Lazarus Station | In a medical station on the wall in the corridor shortly after picking up the heavy pistolExact spot: being checked | Being checked | |
| Wall Safe Credits | Lazarus Station | A hackable wall safe located in the office room shortly before meeting JacobExact spot: being checked | Speaking to Miranda and boarding the shuttle | |
| Datapad Credits | Lazarus Station | Found on a desk in the server room shortly after joining up with Jacob TaylorExact spot: being checked | Speaking to Miranda and boarding the shuttle | |
| Wall Safe Credits | Lazarus Station | Found inside the room where you meet the Cerberus operative WilsonExact spot: being checked | Speaking to Miranda and boarding the shuttle | |
| Medi-gel | Lazarus Station | Inside the medical station on the wall next to Wilson when you first find him injured | Being checked | |
| Heavy Weapon Ammo | Freedom's Progress | Next to a medical station inside the first modular habitat entered after landing | Being checked | |
| Refined Iridium | Freedom's Progress | In an open crate inside the prefabricated building just past the first wave of LOKI mechsExact spot: being checked | Being checked | |
| Wall Safe (Credits) | Freedom's Progress | Mounted on the wall inside the Quarian outpost command room before opening the hangar blast doorExact spot: being checked | Being checked | |
| Med-Kit | Freedom's Progress | On the floor near the control console in the hangar overlooking the YMIR Mech arena | Being checked | |
| M-15 Vindicator Assault Rifle | Omega | On a couch in Archangel's stronghold, right near where Garrus is positioned | Being checked | |
| M-9 Tempest Submachine Gun | Omega | In the clinic area during Mordin's recruitment mission, lying on a table in the mercenary-held roomsExact spot: being checked | Being checked | |
| Assault Rifle Damage Upgrade | Omega | Downloaded from a wall terminal inside Archangel's baseExact spot: being checked | Being checked | |
| Heavy Weapon Ammo Upgrade | Omega | Hacked from a computer terminal in the plague district near Mordin's clinicExact spot: being checked | Being checked | |
| Submachine Gun Damage Upgrade | Omega | Found on a datapad inside the mercenary quarters during the Archangel recruitment lineExact spot: being checked | Being checked | |
| Heavy Weapon Ammo | Horizon | In a datapad inside the first colony building Shepard breachesExact spot: being checked | Being checked | |
| M-443 Particle Beam | Horizon | Found lying on the ground near an inactive defense turret inside the settlementExact spot: being checked | Being checked | |
| Biotic Damage Upgrade | Horizon | In a research terminal inside the quarantine lab building before reaching the space cannonExact spot: being checked | Being checked | |
| Heavy Skin Weave Upgrade | Horizon | In a research terminal located near the transmitter array where Mechanic Delan is hidingExact spot: being checked | Being checked | |
| Submachine Gun Damage Upgrade | Illium | Hacked from a computer terminal inside the Dantius TowersExact spot: being checked | Being checked | |
| Heavy Weapon Ammo | Tuchanka | Next to the terminal in the hospital during Mordin's loyalty mission | Being checked | |
| Krogan Shotgun (Claymore) | Tuchanka | Looted from the weapon crate during Grunt's Rite of Passage (exclusive to Soldier/Vanguard Shepard or Grunt) | Being checked | |
| Combustible Manifold | Tuchanka | Located on the ground near the crashed truck on the way to the Blood Pack baseExact spot: being checked | Being checked | |
| Assault Rifle Damage Upgrade | Tuchanka | Salvaged from discarded rifle parts in the Clan Werloc base during Mordin's loyalty missionExact spot: being checked | Being checked | |
| False Positive ID | Citadel (Return visit) | Found during Garrus's loyalty mission or on Level 27 near the transport terminalExact spot: being checked | Being checked | |
| Heavy Weapon Ammo Upgrade | Omega (Return visit) | Found inside the transport ship terminal during Garrus: Eye for an EyeExact spot: being checked | Being checked | |
| Sniper Rifle Damage Upgrade | Omega (Return visit) | In the VIP lounge area during Thane's recruitment missionExact spot: being checked | Being checked | |
| Assault Rifle Damage Upgrade | Omega (Return visit) | Salvaged from an encrypted terminal during Samara's recruitment missionExact spot: being checked | Being checked | |
| Submachine Gun Damage Upgrade | Illium (Return visit) | Hackable terminal located in the cargo transfer area during Miranda's loyalty missionExact spot: being checked | Being checked | |
| Heavy Pistol Damage Upgrade | Illium (Return visit) | Terminal near the VIP lounge offices during Thane's loyalty missionExact spot: being checked | Being checked | |
| Medi-Gel Capacity Upgrade | Illium (Return visit) | Medical terminal in the transit terminal during Miranda's loyalty missionExact spot: being checked | Being checked | |
| Refined Element Zero | Tuchanka (Return visit) | Near the exit door of the medical facility during Mordin's mission preparationsExact spot: being checked | Being checked | |
| Advanced Weapon Training (or unique Heavy Weapon / special weapon) | Collector Ship | On the control console platform early in the ship before reaching the central terminalExact spot: being checked | Being checked | |
| Heavy Skin Weave Tech Upgrade | Collector Ship | Retrieved from a Collector terminal examined on the lower pathwaysExact spot: being checked | Being checked | |
| Damage Protection Tech Upgrade | Collector Ship | Found by salvaging Collector research terminals along the escape routeExact spot: being checked | Being checked | |
| Heavy Weapon Ammo | Purgatory | Next to the door leading into the first cell block after Kuril springs his trap | Being checked | |
| Shotgun Damage Upgrade | Purgatory | On a terminal in the security control room overlooking the cryo baysExact spot: being checked | Being checked | |
| Credits | Purgatory | Wall safe in the security office near the beginning of the prison sectionExact spot: being checked | Being checked | |
| Sniper Rifle Damage | Korlus | Researched at a terminal inside a shipping container shortly after meeting the wounded mercenaryExact spot: being checked | Being checked | |
| Krogan Vitality | Korlus | Researched at a terminal located in Okeer's laboratoryExact spot: being checked | Being checked | |
| Heavy Weapon Ammo | Korlus | Scanned from a PDA on the floor in the room just before exiting to the final landing pad | Being checked | |
| Heavy Weapon Ammo Upgrade | Haestrom | On a terminal in the garage area near the downed gunshipExact spot: being checked | Being checked | |
| Sniper Rifle Damage Upgrade | Haestrom | On a damaged geth rifle in the control room where you disable the blast doorsExact spot: being checked | Being checked | |
| Heavy Pistol Damage Upgrade | Haestrom | On a terminal in the room where you meet Kal'ReegarExact spot: being checked | Being checked | |
| Geth Pulse Rifle | Haestrom | Found on the ground near the geth Colossus after the battle (Hardcore/Insanity difficulty only)Exact spot: being checked | Being checked | |
| Heavy Weapon Ammo | Derelict Reaper | Stored in a computer terminal in the early research corridors before the first major exterior bridgeExact spot: being checked | Being checked | |
| Sniper Rifle Damage Upgrade | Derelict Reaper | On a terminal in the catwalk section near an indoctrinated crew audio logExact spot: being checked | Being checked | |
| Heavy Skin Weave Upgrade | Derelict Reaper | Retrieved from a research terminal in the lower processing areaExact spot: being checked | Being checked | |
| Element Zero Cache | Collector Base | On the main path shortly after disembarking the Normandy in the infiltration sectorExact spot: being checked | Being checked | |
| Refined Iridium | Collector Base | In an alcove near the first heat vent consoleExact spot: being checked | Being checked | |
| Refined Platinum | Collector Base | Located along the walkway before the biotic barrier escort sequenceExact spot: being checked | Being checked | |
| Refined Palladium | Collector Base | Near the platform terminal prior to the final descent to the central coreExact spot: being checked | Being checked |
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